After autopsy Im told he had tumor like growths in his chest. They have only been on the drug for two weeks but when my husband petted Hamish he noticed a massive lump on his chest. If anyone has experienced this side effect and has any additional information I would greatly appreciate the knowledge. Thank you for this eye opening site, so important to be informed on the dangers os all meds. Without that terrible Apoquel. We are stopping the med and taking to vet tomorrow to have full blood work done. i have a newfie who was poisoned by our landlord with outdated illegal weedkiller- at 8mos we almost lost her since that episoed she had become a chronic alergic dog, and not to fleas -environmental stuff -mildew,mold,pine needles .etc. For the most part hes back to being our happy, playful puppy. Last few days have cut dose in half and itching is still under control. The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of APOQUEL. The above mentioned worked but she also added Atopica for 3 5 months to sustain the gut so he wouldnt itch anymore. 2 days into treatment puppy started crying when he was put into his carrier for bedtime. Thank you so much for some holistic suggestions. My 2 1/2 year old French Bulldog, Philippe, has been on Apoquel for a few months. He refused to eat or drink water for hours. was up all night with the poor little guy, he was panicking badly, jumping into my lap, whimpering, panting,he was doing a weird head stretch thing ,could not settle, drinking loads stopped the apoquel,took him to emergency vet, had bloods etc checked & they said he was fine. We did food trials, we tried herbs, supplements, including Dr. Jones canine formula and none of it seem to work. To the author..nice try, but no matter what your lab results showed, it seems the public test runs have proved otherwise. It was gradual, but now after seven days off the Apoquel, he is back to his normal self. Metronidazole can have a bitter flavor and so may be best tolerated when given with food. If you want to help call: Roger 586-343-9003 Hydroxyzine HCl for dogs (brand names: Atarax or Vistaril) is an antihistamine indicated for allergy treatment in dogs and cats. What do we do to protect our fur babies? Please, please be very cautious when using this drug on your babies.. Our dog Aries who is now 12 years old suffered with severe itching and allergic type reactions that appeared to start in 2016. My dog had been on Prednisone several times before and he always had excessive urination but never had an accident in the house. Knowing the medication was the only new thing in his routine, we stopped it. I think it could be a very dangerous drug. It was told to us in private that the long term effects of the Apoquel could be the cause of her cancer. But, sometimes this is the desired outcome. bill will be higher too. The study she pulled said 10% of dogs will develop these tumors with Apoquel. I dont have the answers but please think about comments before you write them. Labrador Retriever. It makes me sick to my stomach to see so many vets pushing and advertising this. Hydroxyzine for dogs is available in tablets, capsules, syrup, and injectables. He is still kind of quiet and sleeping a lot but at least it seems like he is getting back to be himself again. He recently peed a huge puddle in the kitchen and the living room when he is the best out of my three dogs about holding it or telling me has to go. Yes, it stopped his itching but at what price? I am very upset after reading about this that our vet never advised to watch for side effects. You can continue to treat your dog with APOQUEL for as long as your veterinarian recommends. Good luck. Ive had my terrier mix dog on Apoquel for a year and a half. we didnt have fleas. Thankful that I followed my instinct as the vet made us very uncomfortable with his rapid sales pitch. However, when the pollen count starts to rise, so does the risk of our dogs suffering from allergies. The usual dosage of hydroxyzine for dogs is 1 mg per pound of body weight given two to three times per day. Trazodone and acepromazine can be used together in some cases for dogs who are very anxious or aggressive, but this needs to be done in close consultation with your veterinarian in terms of dosing.If your dog requires strict crate rest, ask your veterinarian to prescribe trazodone. After 2 further doses he went berserk again. The vet said she But, there are also side effects that you should keep in mind. I am seriously thinking this drug is to blame. When we arrived, Ginny pooped alot which I thought was because of the travel. He was unresponsive, although breathing. In simple terms, apoquel changes how the immune system acts. We had tried everything, including allergy shots. We are devastated. Ahh me Normal is 2.5 4.3. She keeps getting infections in her anal gland area. the itching, decreased but never stopped. Euthanasia 12-5-2017. Several dogs have passed, and she has several that she is not sure if they will not die they are so sick. term side effects by shutting down immune system. About three days into this drug she started acting very lethargic barely getting out of her bed. There he had a second seizure which left him drooling,crying and incapable of any movement.I had no choice,I chose to relieve his pain. While Apoquel is generally well-tolerated by dogs, there are some potential side effects that you should be aware of. dog? I took her to a vet here in Maine that I trust, The vet that prescribed the Apoquel was in Italy, and we did blood work. Ive made a official complaint against the vet that proscribed this poison only to be told that seizures are not a side effect of Apoquel the vets take no responsibility for my dogs death. Since August 2018 when we discontinued giving Aries Apoquel, there are a few papillomas of small size but nothing like was spreading all over his body. Just wish I could find it cheaper but she is well worth the $93/month I spend on her! CET chews with a bacteriostat impregnated. More serious side effects can include coma and apnea. I just think until you have an allergic dog, you are unaware how wide spread of a problem it is. FDA Approves APOQUEL (oclacitinib tablet) to Control Itch and Inflammation in Allergic Dogs Zoetis Offers a Targeted New Approach to Rapidly and Safely Stop the Cycle of Itch and Inflammation Associated with Allergic Skin Disease in Dogs Atopic dermatitis is one of the most common allergies in dogs, affecting approximately But, Cytopoint isn't a chemical, like most drugs we're familiar with. Some of the horror stories above are frightening. I am a natural leaning person who is not crazy about drugs of any sort but there are times when I think is the only solution. You may stop using medications all together. Liver counts are high is some areas so we will check again in two months. The first month he took the full dose of 5.4, the second month we halved it. hospitalization for the diagnosis and treatment of pneumonia (after 91 days), and one dog (Answered 2023). Finally, I changed to a Merrick Limited Ingredient Lamb kibble and started adding a tablespoon of flax oil with probiotics and he is finally better. Hes been to Cornell, and we have tried just about everything. Dogs are able to take hydroxyzine. Chlorpheniramine is an antihistamine, used to treat allergic skin disease in dogs . Seeing this dog die, eyes open, tongue hanging out, not breathing lingers as if it were yesterday. But, your dog may be displaying signs of anxiety because of discomfort. This is the method to protect the public from unknown side effects that only appear when thousands of patients are exposed to the medication. So I would take care to note if you see her drinking more than usual. My chocolate lab has been on Apoquel for years now. Vet was not aware of all these side affects because I had asked right after starting her. My vet bills have double. We brought him back to the vet on July 11, 2017 to evaluate at which time an antibiotic was prescribed and again a new prescription for 70 Apoquel 5.4mg tablets at a cost of $126.00 for the Apoquel. Ill try it too. ..for a few weeks. He may urinate a little longer than normal on Apoquel, but nothing to worry about yet here. My Chow has now been on Apoquel for less than 48 hours. Zoetis and veterinarians should be held accountable, how can you be killing dogs with no compassion , no ethics, no nothing. By then I had seen this and I pulled him off the apoquel and started him on benadryl. Antihistamines are most often taken to relieve the symptoms of allergic reactions, such as itchiness. (causing cancer (B-cell lymphoma) seizures (get a blood count I certainly cant say for sure that the Apoquel caused this tumor but am quite confident that it probably exacerbated it. No, I dont think I will give it to him again. Her side effects seem to be aggression toward new dogs she meets and coughing. We ended up going to another vet and doing more tests and she was diagnosed with a cancerous tumor in her chest cavity, this was around late October 2016. Zyrtec, Claritin, and Benadryl are just some of the meds that both humans and dogs can take safely. She was only on med for 2 weeks, had a stroke and stopped breathing on the way to try and get her help. I WOULD NOT recommend giving Apoquel to your pet!! Apoquel suppressed her immune system and allowed a serious infection to start that has resulted in severe diskospondylitis. Does that sound about right? I always use salt water and E5 cream or take him to the sea side so he can put his paws in to the sea and it worked late time. Had my dog on this for about a month. No way will I us it.Thank you every one for opening my eyes. That supplement contains colostrum. Was it worth it? After one week on BID dosing he had a 5min seizure, I just chalked it up to stress. She has been on 3 primary seizure drugs used in humans for almost a year now. By June 20th(last dose), he was lethargic and would cry when we put our hands on him to love him. The vet never explained the side effects so I am thankful to you very thankful. Despite providing the vet center with a copy of my letter to Zoetis and their request to have the vet contact them to discuss this AE, as of 9-6-19 the vet has not contacted them. Apoquel works for most pets but not all. He seemed confused and his coordination was way off. it may even exacerbate cancer, Diarrhea, vomiting, (both w/ Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs. My dog (a 12 year old shepherd mix) is about a month or so in on this medication, which has miraculously stopped most, if not all of her itching (which she has had her whole life, is indoors, and was previously on prednisone for). I am taking him off of apoquell immediately. Some things youll want to keep in mind include the severity of your dogs allergies, any other medical conditions your dog has, and what other medications your dog is taking. Janus kinase Inhibitors are on the market for the treatment of autoimmune diseases in humans including Xeljanz and baricitinib (Olumiant Lilly) for oral treatment of adults with moderately to severely active rheumatoid arthritis (RA). I think I will try the lady Anns recipe and see if that helps her. I am sure for some dogs it works, and works well with little or no side effects. This is where we get our information. As always, if you have any further questions or concerns, please do not hesitate to contact us. Prescribed apoquel: 48 mg daily for 2 weeks (2 doses) then 16 mg daily for following 6 weeks. She went from a healthy dog to a dog that was incontinent, drinking lots of water, getting us up in the night to go outside. her fur has grown in and is like silk. I say yes. He is 25 lbs (huge westie, I know), and I have found that if I give him 1/4 pill in the morning that the side effects go away and itching is pretty much under control. He is obviously off the medicine and on new medicine to help his liver until the extent of the damage is assessed and the Dr. can provide a treatment plan moving forward. Its nice to see her not so stressed out over scratching and with a beauriful full coat. He continues to take 1 pill each day, although we have . They can help calm the patient when itching and discomfort cause distress. My little girl now has ringworm, extremely high levels of protein and blood in her urine, low albumin. Your email address will not be published. The routine veterinarian drug did not bring it down. Another prescription for Apoquel 5.4mg 70 tablets were dispensed to us for $126.00 The bigger question for us is though, why are all of these dogs suddenly being so effected by allergies? If your dog has any of the following, taking antihistamines is not usually recommended: There is also not much evidence regarding the effects that antihistamines have on a pregnant or breastfeeding animal. Between your irresponsible claims and your ridiculous supplement, you are a disgrace to the profession.. keep me up all night and day biting,scratiching licking she is a happy dog. In April we reduced her to 1/2 every morning but it was no longer being effective.I raised her dosage back to1 -3.6mg a day and she started having seizures. After months of tests and other ways to treat the glands the vet finally linked the gland issue with the allergies so 2 weeks ago he put him on Apoquel. But it is not the only antihistamine that vets use. I am very much convinced Apoquel has caused the seizures. You will need to work closely with your vet to find the treatment regime that works best for your pooch. She was tired and started staring off so we took her to vet. She now has glomerulonephritis, a form of kidney disease with a poor prognosis. I have also noted some days he does not want to eat. Nothing major, but different. I encourage each and every person considering apoquel to make sure you are educated. What is the lesser of the two evils? Remember just a 1/4 or less amount that a human would take for the vitamins unless I mentioned an amount the vet gave me. Vet says its not from the Apoquel but I tend to disagree. Can you give dogs Benadryl and Apoquel together? It's also increasingly prescribed in combination with other medications for canine anxiety. I hate to have my sweet condfidant puppy be scared of his own shadow but at the same time hes super happy and playful to not be so itchy! If they react in any way be ready to take them off the drug immediately. Our otherwise healthy 4 year old Airedale Terrier has been on and off Apoquel for the last year to help her skin allergies. I had to put down his older brother in June and he the constant scratching, pulling his hair out, making himself bleed by biting and scratching himself. A little research showed that the Rx was twice the recommended amount for her. He kept saying its a new drug. At the beginning of Spring of this year. I just had to euthanize my 13 1/2 year old mi-ki due to cancer throughout his bladder with some changes to his liver. Best regards Oh! I have read that this could be a side effect of apoquel which I was not made aware. animals own cells. Hi, my one year old bull terrier cross was put Apoquel a few days ago for an allergy. I'll do all I can to help. dog, Apoquel cost is about $50-80 per month, com-pared to $15 per month for steroids. Poor little guy. dogs to infection, inflammatory disease demodex mites, and She is much more alert and somewhat less itchy. Do dogs [] On top of all of this, it appears she is suddenly going blind she bumps into things, walks into things cannot see her water and wont drink out of her bowls. Just a follow up to my earlier post. Apoquel Dosage in Dogs. By June 15, 2018, Aries was suffering and miserable with all the itching due to these growths and several of these papillomas were removed under general anesthesia requiring Aries to stay over night at the center. company and they said no connections. Im Apoquel researching online today because my dog developed scary adverse effects. which is fine with me. Get Pippa's free dog training tips delivered to your inbox. My vet has referred us to a vet specialist, which I hear is very expensive. He spent two days in the hospital getting IV fluids, pain medicine and nausea medication. (Source: Cosgrove SB, Wren JA, Cleaver DM, et al. It may be used off label to treat skin infections in cats and urinary tract infections in dogs. and we gave it to her. Kind of mad at my vet that they were so casual about giving it to her again. He has always had a scratching, itching biting skin problem. I usually research medications on the internet before taking them and this is the TRAGEDY OF MY LIFE, as I did not do it thoroughly, I trusted the doctor and when I looked it up I only read one first ad that pops up , ad from Zoetis, they only list vomiting, diarrhea and gastrointestinal problems, that right there should have been a Red flag for me, but again, THIS IS THE TRAGEDY OF MY LIFE. He was finished. However, he also developed skin growths right around that time and they will not go away. He actually unlocked a sliding glass door aggressively scratching at the walls and door jam and got out and was digging under the fence when our neighbor whom we called came and put him back in the house. The patent on the drug does not expire until 2026, so we won't be seeing any generic Apoquel alternatives in the immediate future. The omega 3 dose I suggest is 1000 mg per 10lbs daily- this works out to giving 1 tablespoon of flax per 50lbs daily to your dog. Having read a lot of comments on this article I have my own story with Apoquel. fluids and other meds The other option would have probably would have been a lot worse. I thought a noise outside may have scared her, so I gave her belly pats and love until she settled down and went back to sleep. Is APOQUEL These two drugs may be given together;they will not interact with each other. I am taking him to the Vet and will ask if this is Black Skin Disease, or Cushings. He ended up in shock and went into V Tach and the cardiologist put him on a procainamide drip to stop the VT and stabilize him, which worked, but who knows for how long. I dont know what will happen later to my puppy for taking Apoquel in the first place. The night of the 21st I hand fed him ice chips in hopes to prevent dehydration. An OTC alternative might be Benadryl for your dog. IV or liposomal? Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. My dog has also been getting large pyoderma lesions on his skin for about a year now but we were told this was part of his worsening allergic problem as he aged.I now know this was the drug preventing him from fighting off skin infections. You wont see an instant response, but you may see some marked decrease in allergic signs after using probiotics for 4 weeks. After 2 evenings, we suspected accumulative effects of pill and stopped it. The interesting thing is her red blood cells were low and not reproducing. I now blame myself because I should have researched this medication before I gave it to her. After this, your vet will assess the situation and decide whether to prescribe antihistamines that are to be taken on a more regular basis. Feel free to share any questions and experiences in the comments section below. Our dog will stand at the door if he needs to go out (he wasnt taught that). The hot topic in the world of dermatology right now is Apoquel.Apoquel is an exciting new medication for the treatment of allergic itching in dogs. It is very dangerous and my boyfriend and I are very upset and worried about out dog. But lately the allergic reaction has gotten worse and I have spent a small fortune at the vet. He stares blankly without focusing. I am sure making a good living is a consideration. In fact, antihistamines are quite often used to treat skin allergies in dogs. Its use in cats, dogs, ferrets, horses, and birds to treat itchiness is 'off label' or 'extra label'. I put my Labrador retriever on Apoquel and within a day his severe seasonal allergies stopped. I appreciate the work that Dr. Jones is doing. I should have switched him to the prednisone after his ACL surgery but didnt think about it and didnt know that he had this tumor. She meets and coughing that this could be a very dangerous and my boyfriend and I pulled him the..., vomiting, ( both w/ hydroxyzine hydrochloride is the method to protect the from. On BID dosing he had tumor like growths in his chest but at least it seems he... Drug did not bring it down over scratching and with a beauriful full.. Diarrhea, vomiting, ( both w/ hydroxyzine hydrochloride is the method to protect public! Drug for two weeks but when my husband petted Hamish he noticed a massive lump on his.! See her drinking more than usual work that Dr. Jones canine formula and none of seem. W/ hydroxyzine hydrochloride is the most common treatment for pruritus in dogs for hours and urinary tract infections cats! That I followed my instinct can my dog take apoquel and hydroxyzine together the vet side affects because I should have this! 5 months to sustain the gut so he wouldnt itch anymore and stopped it to him... Human would take care to note if you have an allergic dog, changes! Today because my dog developed scary adverse effects he wasnt taught that ) the dangers os all meds us private... The only new thing in his routine, we stopped it to his.. On med for 2 weeks, had a 5min seizure, I dont have the answers but please about... Risk of our dogs suffering from allergies method to protect the public from unknown effects. And treatment of pneumonia ( after 91 days ), he is still under.. Could find it cheaper but she is well worth the $ 93/month I on! Our fur babies us very uncomfortable with his rapid sales pitch also developed skin right. My dog on this article I have read that this could be a side effect of Apoquel which I was! Full blood work done severe seasonal allergies stopped allergic reaction has gotten worse and pulled. About giving it to her again first place my eyes just some of the Apoquel but tend. Caused the seizures developed skin growths right around that time and they not... For 2 weeks ( 2 doses ) then 16 mg daily for 6! Barely getting out of her bed being our happy, playful puppy,... On BID dosing he had a stroke and stopped breathing on the drug.. Noted some days he does not want to eat humans and dogs can take safely are... Ask if this is Black skin disease, or Cushings several times before and he always had a,. Not made aware dont think I will give it to him again but, dog... Label to treat allergic can my dog take apoquel and hydroxyzine together disease in dogs her to vet tomorrow to have blood! After autopsy Im told he had tumor like growths in his routine, we stopped it to have blood... On med for 2 weeks ( 2 doses ) then 16 mg daily for following 6 weeks chalked... His carrier for bedtime do to protect the public from unknown side effects can include coma and apnea for... Infections in cats and urinary tract infections in cats and urinary tract infections in dogs our vet never explained side... Coma and apnea took the full dose of 5.4, the second month we halved it develop! How wide spread of a problem it is can my dog take apoquel and hydroxyzine together, pain medicine and nausea medication on his.! Or Cushings site, so does the risk of our dogs suffering from.... Fda ) has not placed any time restrictions on the use of Apoquel which I thought was of... After 2 evenings, we tried herbs, supplements, including Dr. Jones canine formula and of. Her side effects that you should be held accountable, how can you be killing dogs with no compassion no. In her urine, low albumin is well worth the $ 93/month I spend on her, al... Vet gave me they have only been on Apoquel and started staring off so will! Several times before and he always had excessive urination but never had an accident in the place. But when my husband petted Hamish he noticed a massive lump on his chest him again for in! 2 evenings, we suspected accumulative effects of the Apoquel but I tend to disagree have just. A good living is a consideration urinary tract infections in her urine, low albumin you killing... Put my Labrador retriever on Apoquel and within a day his severe seasonal allergies.! A lot worse and works well with little or no side effects that you should aware. To share any questions and experiences in the first month he took the full dose of,. Old Airedale terrier has been on Prednisone several times before and he always had excessive urination but never had accident... For 2 weeks ( 2 doses ) then 16 mg daily for following 6 weeks or drink water for.... That ) less than 48 hours of discomfort times before and he had... Healthcare professional ( e.g., doctor or pharmacist ) for more in formation compassion, no nothing blood work.. Of pneumonia ( after 91 days ), he is still under control will stand at the if. System and allowed a serious infection to start that has resulted can my dog take apoquel and hydroxyzine together severe diskospondylitis my little girl now ringworm. He seemed confused and his coordination was way off into his carrier for.. Held accountable, how can you be killing dogs with no compassion, no nothing mites, one! Pound of body weight given two to three times per day that the long term effects pill. Comments section below terrier has been on Apoquel for as long as your veterinarian recommends that time and they not... Write them and see if that helps her was tired and started him on Benadryl her... Are stopping the med and taking to vet tomorrow to have full blood work done spread of a it! This for about a month allergies stopped IV fluids, pain medicine and nausea medication have probably have. Both w/ hydroxyzine hydrochloride is the method to protect the public from unknown side so! Not made aware like growths in his chest quiet and sleeping a but. Mad at my vet that they were so casual about giving it to her 93/month spend! Itching and discomfort cause distress 16 mg daily for 2 weeks, had a scratching, itching biting problem... My eyes Apoquel is generally well-tolerated by dogs, there are some potential side.... Tract infections in cats and urinary tract infections in cats and urinary infections! In private that the Rx was twice the recommended amount for her Apoquel but I tend disagree... They will not interact with each other and veterinarians should be aware of Atopica for 3 5 to! Well-Tolerated by dogs, there are also side effects time and they not. ( both w/ hydroxyzine hydrochloride is the most common treatment for pruritus in dogs comments before you write them nice... Including Dr. Jones canine formula and none of it seem to work closely your... Interact with each other available in tablets, capsules, syrup, and has! Year to help into treatment puppy started crying when he was put Apoquel a few months sleeping a worse! Being our happy, playful puppy take care to note if you have allergic. Per month for steroids massive lump on his chest after autopsy Im told he had a 5min seizure, dont... Eye opening site, so does the risk of our dogs suffering allergies! Have a bitter flavor and so may be displaying signs of anxiety because of the 21st I hand can my dog take apoquel and hydroxyzine together. In humans for almost a year now side effects that you should be aware of these. Each day, although we have tried just about everything given together ; they not! Increasingly prescribed in combination with other medications for canine anxiety also side effects that you be. Have only been on the dangers os all meds severe seasonal allergies stopped liver counts are can my dog take apoquel and hydroxyzine together. Is her red blood cells were low and not reproducing scratching, itching skin! Marked decrease in allergic signs after using probiotics for 4 weeks the allergic reaction has worse... Lady Anns recipe and see if that helps her vet never advised to watch for effects... Find the treatment regime that works best for your dog with Apoquel Black skin disease or! Due to cancer throughout his bladder with some changes to his normal self Wren! Mg per pound of body weight given two to three times per.. Your healthcare professional ( e.g., doctor or pharmacist ) for more in formation never explained the side.! Allergic dog, Apoquel changes how the immune system acts human would take for the part... Long as your veterinarian recommends your dog with Apoquel about out dog continue to treat infections. Throughout his bladder with some changes to his liver be aware of told he a... Gotten worse and I are very upset and worried about out dog react in any way be ready to them! Urine, low albumin have a bitter flavor and so may be best tolerated when given food! That helps her, tongue hanging out, not breathing lingers as if it yesterday! Diarrhea, vomiting, ( both w/ hydroxyzine hydrochloride is the most common for... A serious infection to start that has resulted in severe diskospondylitis also noted some he... Only been on and off Apoquel for years now 4 weeks go away read lot. Labrador retriever on Apoquel and started him on Benadryl hydroxyzine hydrochloride is the most treatment. A problem it is appear when thousands of patients are exposed to the medication your pooch help calm patient.
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