J Urol. MRI-TULSA resulted in an 88% reduction of viable prostate tissue volume. Kenkhuis MJA, Bakker M, Bardi F, ET AL. These Medical Policies serve as guidelines for health care benefit coverage decisions, which may vary according to the different products and benefit plans offered by BCBSIL. Updated Discussion/General Information and Reference sections. CPT codes Dx codes 76801 76802 D25, D25.0, D25.1, D25.2, D25.9, O0900, O0901, O0902, O0903, O09511, O09512, 2014; 96(9):743-751. The study also included a crossover component; 17 of the 23 individuals in the placebo group who did not complete follow-up chose to receive rescue MRgFUS after a lack of response to placebo. New 2020. Blana A, Murat FJ, Walter B, et al. 2021; 205(3):769-779. BJU Int. ; AUA Prostate Cancer Clinical Guideline Update Panel. American College of Radiology (ACR). June 7, 2018. J Urol. Assessment of chorionicity is most accurate early in pregnancy and, because of the increased rate of complications associated with monochorionicity, determination of chorionicity by the late first trimester or early second trimester is important for counseling and caring for women with multifetal pregnancies. These resources can help members understand their maternity benefits. Anthem has stopped covering patients in nine states 1 for MRI and CT scans performed in hospital outpatient settings - unless the exam qualifies for an "exception." On Nov. 15, Anthem will start retroactive reviews of MRI and/or CT services done in emergency departments in Missouri, Ohio and Kentucky. ACOG Practice Bulletin Number 171. High intensity focused ultrasound (HIFU): A surgical procedure that uses focused high energy sound waves to destroy target tissues in the body. Please enter a valid 5-digit Zip Code. By March 2018, Anthem (Blue Cross/Blue Shield) will require that MR and CT scans considered "not medically necessary" be performed at freestanding medical imaging facilities in order to be covered. 2021; 127(5):544-552. In addition, eligible participants reported a numerical rating scale (NRS) pain score of 4 or greater in spite of maximal pain medication therapy, and a score of 7 or less on the Mirels fracture risk scale. 2018; 51(4):463-469. This document addresses ultrasound ablative therapy for the treatment of oncologic conditions. The guideline addresses several non-extirpative therapies and concluded that these therapies, including HIFU, are investigational for the treatment of renal masses. High-intensity focused ultrasound for treatment of pancreatic cancer: a systematic review. 2015; 2015(7):CD007058. Available at: Centers for Disease Control and Prevention (CDC). Thuroff S, Chaussy C. High-intensity focused ultrasound: complications and adverse events. The document header wording updated from Current Effective Date to Publish Date. Updated Discussion/General Information, References and Websites for Additional Information sections. For other common visits, this is what you'll pay with PPO. The new Multiple Delivery policy has the same . 2020; 22:79-87. 2013; 48(6):351-358. When services are Not Medically Necessary:For the procedure and diagnosis codes listed above when criteria are not met or for all other diagnoses not listed; or when the code describes a procedure or situation designated in the Clinical Indications section as not medically necessary. J Endourol. Clin Oncol (R Coll Radiol). 2015; 102(3):182-193. Joo B, Park MS, Lee SH, et al. The Centers for Medicare and Medicaid Services (CMS) released an updated Relative Value file Jan. 5, that includes updated reimbursement for the neuromuscular ultrasound codes 76881, 76882 and 76883. Guideline for the management of clinically localized prostate cancer: 2007 update. 2016; 19(3):311-316. The updated file enables providers to separately bill for the professional component (26) and the technical component (TC). Management of preterm labor. The American College of Obstetricians and Gynecologists (ACOG) 2018 Practice Bulletin Ultrasound in Pregnancy lists the following recommendations: The following conclusions are based on good and consistent evidence (Level A): The following conclusions are based on limited or inconsistent evidence (Level B): The following conclusion and recommendation are based primarily on consensus and expert opinion (Level C): The American College of Radiology (ACR), the American Institute of Ultrasound in Medicine (AIUM), ACOG, the Society for Maternal Fetal Medicine (SMFM), and the Society of Radiologists in Ultrasound (SRU) practice parameter (2018) notes: A standard obstetrical ultrasound examination in the first trimester includes evaluation of the presence, size, location, and number of gestational sac(s). Researchers used the visual analog pain score (VAS) to measure pain levels. You should contact Anthem Blue Cross and Blue Shield directly to appeal denial of coverage for medical claims by calling 1855- -641-4862. National Coverage Determination: Ultrasound diagnostic procedures. 2009; 101(1):19-26. 2010; 17(8):715-719. Available at: U.S. National Library of Medicine. The use of HIFU in the setting of breast cancer treatment may not allow for an adequate collection of tumor specimens to evaluate the tumor histopathology. Insurance coverage for whole-breast ultrasound is evolving. The pain severity score was significantly reduced from a baseline mean of 7.1 (Standard Deviation[SD] 2.08) (4-10; 95% confidence interval [CI], 6.07-8.15), to 2.5 (SD 1.4) (0-5; 95% CI, 1.81-3.2) at 1 month. November 17, 2019. American College of Obstetricians and Gynecologists (ACOG) and Society for Maternal Fetal Medicine (SMFM). Available at: High Intensity Ultrasound System For Prostate Tissue Ablation (Focal One). 2015; 2015(6):CD001451. Ideally the ultrasound is done at the same appointment as the screening mammogram. HIFU or MRgFUS has also been studied as a potential treatment of various cancers. The system protects the urethra and rectum via a water cooling system pumped through the applicator. Updated Coding section to include ICD-10-CM diagnosis codes Z36.0-Z36.9. CO CHEIBA Custom Blue Priority PPO/BluePreferred Plan F 01 -20 1 of 15 Summary of Benefits and Coverage: What this Plan Covers & What You Pay For Covered Services Coverage Period: 01/01/2021- 12/31/2021 Anthem Blue Cross and Blue Shield: Prime Blue Priority PPO Focal therapy with high-intensity-focused ultrasound in the treatment of localized prostate cancer. 2004; 7(4):289-294. For more information about your rights, look at the explanation of benefits you will receive for that medical claim. Our radiologists are among the most . Specific findings associated with congenital Zika syndrome include intracranial calcifications, microcephaly, ventriculomegaly, arthrogryposis; abnormalities of the corpus callosum, cerebrum, cerebellum, and eyes; and other brain abnormalities. Cancer. Bonekamp and associates (2019) performed a quantitative analysis of viable prostate tissue volume reduction at 12 months post-procedure. HAIFA, Israel- MIAMI, Dec. 22, 2022/CNW/ -- Insightec, a global healthcare company dedicated to using acoustic energy to transform patient care, announced today that Anthem is the third national. Beerlage HP, van Leenders GJ, Oosterhof GO, et al. Crouzet S, Blana A, Murat FJ, et al. 2015; 194(1):114. In the first phase III study published, Hurwitz and colleagues (2014) conducted a randomized, placebo-controlled, single-blind, multicenter, pivotal trial which included 147 participants with bone metastases from breast, prostate, kidney, lung or other primary tumors. Visit our official site today for more details. Urology. Hemi salvage high-intensity focused ultrasound (HIFU) in unilateral radiorecurrent prostate cancer: a prospective two-centre study. This early study focused on safety and technical feasibility rather than clinical outcomes. The study has several methodological flaws, including lack of a comparison group, and uncertainty regarding the percentage of subjects who completed the follow-up period. Ann Surg Oncol. The authors concluded, Although newer modalities hold promise, we need higher quality studies to assess patient important outcomes to guide evidence-based clinical practice.. An mpMRI, a transrectal ultrasound guided biopsy and a cystoscopy were performed at 12 months post-procedure. Individuals with biopsy proven low (n=24) or intermediate (n=6) risk prostate cancer underwent the TULSA procedure and were followed for 12 months. 2011; 3(3):329-338. Minerva Urol Nefrol. Br J Surg. Updated Coding section with additional diagnosis codes D25.0-D25.9, O26.872-O26.879, O99.210-O99.213, O99.810. Systematic review of high-intensity focused ultrasound ablation in the treatment of breast cancer. 2017; 3:CD012600. Approved May 19, 2020. Focal high intensity focused ultrasound of unilateral localized prostate cancer: a prospective multicentric hemiablation study of 111 patients. In November, the FDA approved the use of Ablatherm (Maple Leaf; Toronto, Canada) to treat prostate cancer in individuals who previously failed radiation therapy. ACR Appropriateness Criteria. Chin JL, Billia M, Relle J, et al. Eur Urol. This document does not address nuchal translucency. Recommendations for the management of a pregnant individuals with suspected Zika virus infection include: The 2021 CDC guideline on the treatment of sexually transmitted infections includes management recommendations for individuals who are diagnosed with text in the second half of pregnancy. ISUOG Interim Guidance on ultrasound for Zika virus infection in pregnancy: information for healthcare professionals. A clinically significant biopsy was reported in 34% (10/29) of participants with 59% (17/29) of participants reporting any positive biopsy. The location you tried did not return a result. 2017; 69(1):93-100. AIUM Practice Parameter for the Performance of Detailed Second- and Third-Trimester Diagnostic Obstetric Ultrasound Examinations. The clearance was based upon the Ablatherm device as the predicate device. The overall survival (OS) rate was 80%, the progression-free survival (PFS) rate was 94%, and the disease-specific survival rate was 97%. Accessed on September 13, 2022. While the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines (CPG) in Oncology for Adult Cancer Pain (V2.2022) document notes that the palliative effects of HIFU have been demonstrated in several small studies, no recommendation for or against the use of HIFU for pain palliation was given. Gelet A, Chapelon JY, Poissonnier L, et al. Non-Contact Ultrasound Treatment for Wounds; Non-Oncologic Uses of Rituximab (Rituxan) Nutritional Treatment of Childhood Medical Conditions; Ophthalmologic Techniques for Evaluating Glaucoma; Optical Diagnostic Devices for Evaluating Skin Lesions Suspected of Malignancy ; Oral Lesion Identification System (ViziLite, Velscope) Primary pain palliation and local tumor control in bone metastases treated with magnetic resonance-guided focused ultrasound. Available at: Centers for Medicare and Medicaid Services. Lumiani A, Samun D, Sroka R, Muschter R. Single center retrospective analysis of fifty-two prostate cancer patients with customized MR-guided transurethral ultrasound ablation (TULSA). Ultrasound is currently being used as a therapeutic treatment, for example, lithotripsy to disintegrate kidney stones. Routine Tests During Pregnancy. Transurethral ultrasound ablation (TULSA), which delivers directional thermal ultrasound via a catheter inserted into the urethra, is specific to prostate cancer. MPTAC review. Albisinni S, Aoun F, Bellucci S, et al. The benefits and limitations of ultrasonography should be discussed with all patients. Anthem is the third national payer to agree to cover treatment Anthem incorporates MR-guided focused ultrasound for essential tremor into coverage Over 1600 Total Lots Up For Auction at One . In an intent-to-treat analysis, 63% (72/115) were reported to have a complete histological response and had no evidence of cancer. Chen L, Wang K, Chen Z, et al. However, the change from baseline in MEDD intake was not statistically significant, although the authors noted a trend towards a statistically significant change. 2012; 118(17):4148-4155. The mean reduction in the NRS score was significant between MRgFUS and placebo (3.6 3.1 versus 0.7 2.4). 2014; 84(5):1157-1162. In brief: classifications in brief: Mirels' classification: metastatic disease in long bones and impending pathologic fracture. Revised 2020. Bone metastases are common in breast and prostate cancer (Liberman, 2009). U.S. Food and Drug Administration (FDA). Revised title from High Intensity Focused Ultrasound (HIFU) for Oncologic Indications to Ultrasound Ablation for Oncologic Indications. Li CC, Wang YQ, Li YP, Li XL. $0 plans in select areas. We reserve the right to review and update Clinical UM Guidelines periodically. Ultrasound is currently being used as a therapeutic treatment, for example, lithotripsy to disintegrate kidney stones. The five HIFU trials included a total of only 136 individuals. Ahmed HU, Zacharakis E, Dudderidge T, et al. According to the FDA labeling, a nonunion is considered to be established when the fracture site shows no visibly progressive signs of healing. Updated Discussion/General Information, References and Websites for Additional Information sections. Palliative treatment: Treatment given for relief of symptoms and pain rather than attempting to cure. -12/31/2022 Summary of Benefits and Coverage: What this Plan Covers & What it Costs Coverage for: Individual + Family | Plan Type: HMO The Summary of Benefits and Coverage (SBC) document will help you choose a health plan.The SBC shows you how you and the plan would share the cost for covered health care services. Anttinen M, Mkel P, Viitala A, et al. First clinical experience of intra-operative high intensity focused ultrasound in patients with colorectal liver metastases: a phase I-IIa study. Br J Surg. The baseline median PSA of 7.6 ng/ml decreased to 0.23 ng/ml at 12 months follow-up. Eur Urol Open Sci. 2012; 118(12):3071-3078. Urology. Locally recurrent prostate cancer after initial radiation therapy: early salvage high-intensity focused ultrasound improves oncologic outcomes. Although the exact mechanism of analgesic action of MRgFUS in pain palliation is unknown, studies have pointed to a few explanations. These results were not included in the primary efficacy analysis. J Ultrasound Med. The 2021 American Urological Association (AUA) published a guideline on renal mases and localized renal cancer. Search doctors, conditions, or procedures . Ahhhhh! The maternal cervix and adnexa should be examined. Federal statute and subsequent Medicare regulations regarding provision and payment for medical services are lengthy. Available at: U.S. National Library of Medicine. 1999b; 39(1):41-46. MPTAC review. Zhang M, Liu L, Wang J, et al. There were no treatment-related AEs. Updated Discussion and References section. When services are Medically Necessary for routine anatomy screen and dating when criteria are met: Ultrasound, pregnant uterus, real time with image documentation, fetal and maternal evaluation, first trimester (< 14 weeks, 0 days), transabdominal approach; single or first gestation/each additional gestation [includes codes 76801, 76802], Ultrasound, pregnant uterus, real time with image documentation, fetal and maternal evaluation, after first trimester (> 14 weeks 0 days), transabdominal approach; single or first gestation/each additional gestation [includes codes 76805, 76810], Ultrasound, pregnant uterus, real time with image documentation, fetal and maternal evaluation plus detailed fetal anatomic examination, transabdominal approach; single or first gestation/each additional gestation [includes codes 76811, 76812], Ultrasound, pregnant uterus, real time with image documentation, limited (eg, fetal heart beat, placental location, fetal position and/or qualitative amniotic fluid volume), 1 or more fetuses, Ultrasound, pregnant uterus, real time with image documentation, follow-up (eg, re-evaluation of fetal size by measuring standard growth parameters and amniotic fluid volume, re-evaluation of organ system(s) suspected or confirmed to be abnormal on a previous scan), transabdominal approach, per fetus, Ultrasound, pregnant uterus, real time with image documentation, transvaginal. This document addresses the use of maternity ultrasound in the outpatient setting. Transrectal high-intensity focused ultrasound in the treatment of localized prostate cancer. The single-arm, prospective, multi-center pivotal trial, TULSA-PRO Ablation Clinical Trial (TACT), enrolled 115 individuals with intermediate risk (67.0%) or low risk (33.0%) organ confined prostate cancer who underwent whole gland prostate ablation (Klotz, 2021). . Screening for Fetal Aneuploidy. 15727 Anthem Pkwy, Suite 600 . Updated Description, Coding, Discussion and References sections. Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline. Placenta Accreta Spectrum. 2016; 47(4):530-532. BJU Int. Sofuni A, Moriyasu F, Sano T, et al. Postpartum hemorrhage. MedlinePlus. Statement on Biological Effects of Ultrasound in Vivo. Updated Discussion/General Information, Coding and Reference sections. These studies have a number of methodological limitations, including a lack of randomization of participants, a lack of a comparator group and limited follow-up for oncologic outcomes. Transrectal high-intensity focused ultrasound: minimally invasive therapy of localized prostate cancer. Pain palliation in patients with bone metastases using magnetic resonance-guided focused ultrasound with conformal bone system: a preliminary report. Clinical guidelines approved by the Medical Policy & Technology Assessment Committee are available for general adoption by plans or lines of business for consistent review of the medical necessity of services related to the clinical guideline when the plan performs utilization review for the subject. A statistically significant pain response was reported in 70.7% of this group. Cancer. There were no new reported serious AEs. Pickles T, Goldenberg L, Steinhoff G. Technology review: high-intensity focused ultrasound for prostate cancer. Poissonnier L, Chapelon JY, Rouviere O, et al. There are concerns about inconsistent treatment coverage within renal masses resulting in incomplete ablation. Rockville (MD): Agency for Healthcare Research and Quality (US); 2020 Sep. Report No. Uchida T, Ohkusa H, Nagata Y, et al. Palermo G, Totaro A, Sacco E, et al. Evaluation of quality of life outcomes following palliative treatment of bone metastases with magnetic resonance-guided high intensity focused ultrasound: an international multicentre study. Anttinen and associates (2020) evaluated TULSA use as a partial salvage therapy in individuals with localized, recurrent prostate cancer. Bone metastasis: When cancer cells have broken off from the primary tumor and have settled and started growing on bones. J Pharm Bioallied Sci. High-intensity focused ultrasound (HIFU) followed after one to two weeks by radical retropubic prostatectomy: results of a prospective study. In those individuals who reported a decrease in pain levels, 50% (9/18) reported complete relief of pain, with 52% reporting significant pain relief beginning 3 days post treatment. Boccon-Gibod L, Djavan WB, Hammerer P, et al. Similar to prostate cancer, there is a lack of randomized trials comparing HIFU to standard treatment options. Birth Defects Homepage: Diagnosis. J Evid Based Med. Matthew Thornton Health Plan, Inc./Anthem Blue Cross and Blue Shield Coverage for: Individual + Family | Plan Type: HMO Anthem Silver Pathway X Enhanced HMO 5500/20% S05 ($0 Preferred Virtual Care + $0 Select Drugs) The Summary of Benefits and Coverage (SBC) document will help you choose a health plan. Magnetic resonance imaging-guided transurethral ultrasound ablation of prostate tissue in patients with localized prostate cancer: a prospective Phase 1 clinical trial. Updated grammar in medically necessary statement regarding maternal risk factors from including but not limited to, hypertension, diabetes, sickle cell disease preeclampsia), substance abuse, or hyperemesis gravidarum to including but not limited to, hypertension, diabetes or sickle cell disease), preeclampsia, substance abuse or hyperemesis gravidarum. An obstetrical ultrasound in the second or third trimester includes an evaluation of fetal number, cardiac activity, presentation, amniotic fluid volume, placental position, fetal biometry, and an anatomic survey. Elterman D, Li W, Hatiboglu G, et al. Updated Coding section; added ICD-10-CM code ranges O98.111-O98.119, O99.310-O99.313, O99.320-O99.323, O99.330-O99.333. Grade 3 (n=1) and grade 2 (n=3) AEs related to urinary retention and urinary tract infection were reported. No ionizing radiation (x-ray) is used in ultrasound imaging. American College of Radiology (ACR). 2017; 31(1):14-19. Updated Coding section with 10/01/2020 ICD-10-CM changes; added O99.891; removed Q51.20 deleted 09/30/2020. It is likely that both of these treatment effects contribute to pain relief. Assess vaginal bleeding of undetermined etiology; Assess abdominal or pelvic pain of undetermined etiology; Evaluation of fetal condition in late registrants for prenatal care; History of unexplained fetal demise in a previous pregnancy; Assess the fetus in cases with maternal risk factors such as family history of congenital abnormalities, chronic systemic disease (including but not limited to, hypertension, diabetes or sickle cell disease), preeclampsia, substance abuse or hyperemesis gravidarum; Assessment of fetus after abnormal serum Alpha Fetal Protein (AFP), serum screen or multiple analyte serum screen, or cell-free fetal deoxyribonucleic acid (DNA) screening for aneuploidy; Suspected ectopic pregnancy or hydatidiform mole, and to follow hydatidiform mole; Assess the fetus in cases of Rhesus (Rh) isoimmunization and other causes of fetal hydrops; Provide guidance for other testing, such as amniocentesis, chorionic villus sampling, and cordocentesis or procedures such as intrauterine blood transfusions or other in-utero fetal therapeutic procedures. Ultrasound examinations, particularly if obtained soon after onset of infection, may not identify prenatal features of congenital Zika syndrome and structural manifestations can be identified at later points in pregnancy. 2017; 119(6):896-904. The gestational sac is examined for the presence of yolk sac and embryo/fetus (a fetus is generally defined as greater than or equal to 10 weeks gestational age). BJU Int. 2012; 13(6):622-632. Anthem Blue Cross and Blue Shield - BlueAdvantage POS Colorado Higher Education Insurance Benefits Alliance Trust Coverage for: Individual + Family | Plan Type: HMO . HIFU has been evaluated as a minimally invasive treatment of whole gland or a focal treatment of prostate cancer, both in the initial treatment of clinically localized prostate cancer and following recurrence. Blana A, Walter B, Rogenhofer S, Wieland WF. October 2016. J Urol. NCCN Clinical Practice Guidelines in Oncology. The price of a diagnostic mammogram averages from $172 under Medicare to $239 with private insurance. Evaluate for threatened, incomplete, or missed abortion; Non-reassuring fetal heart rate monitoring; Assess amniotic fluid volume in post-term gestation. Prostate cancer is the second leading cause of death with approximately 39,430 deaths in 2018 (Bekelman, 2018). Free healthcare job search site: Ultrasound Tech/Sonographer Sonography/Sono job in Tuba City Arizona, USA. The available evidence does not support that the use of TULSA is clinically appropriate and an effective therapy compared to the standard treatments. HIFU or MRgFUS has also been studied as a potential treatment of various cancers. Taneja SS. Added Websites for Additional Information section. The recommendations are based on limited data. December 2016. Jawad MU, Scully SP. Available at: Antepartum Fetal surveillance. Invest Radiol. Treatment of localized prostate cancer using high-intensity focused ultrasound. Ultrasound abnormalities have been detected in the fetus from 2 to 29 weeks after symptom onset, and therefore, insufficient data are available to define the optimal timing between exposure and initial sonographic screening. Available at: American Cancer Society. Early prospective studies evaluating MRgFUS reported promising results. They determined that Cloyd had ovarian cysts, not appendicitis. There's Still Time To Enroll $0 preventive care. Replaced term women with individual within clinical indications. Alternatively, commercial or FEP plans or lines of business which determine there is not a need to adopt the guideline to review services generally across all providers delivering services to Plans or line of businesss members may instead use the clinical guideline for provider education and/or to review the medical necessity of services for any provider who has been notified that his/her/its claims will be reviewed for medical necessity due to billing practices or claims that are not consistent with other providers, in terms of frequency or in some other manner. The doctors in the emergency room did multiple tests including a CT scan and ultrasound. Find a doctor near you. Updated: June 16, 2022. Anthem has begun denying coverage for . However, residual tumors of less than 10% were found in 29.4% of cases and residual tumors between 10-90% were found in 22.7% of cases. High intensity focused ultrasound as first line salvage therapy in prostate cancer local relapse after radical prostatectomy: 4-year follow-up outcomes. Reformatted Coding section. Klotz L, Pavlovich CP, Chin J, et al. Br J Cancer. . For any of the diagnosis codes listed below for abnormalities and high-risk conditions, and including the following: Encounter for supervision of normal pregnancy [codes 76801, 76805, when criteria are met], Encounter for antenatal screening of mother, When services may be Medically Necessary when criteria are met for known or suspected abnormality of maternal reproductive structure, fetus, or placenta, or fetal viability or other high-risk conditions:For the procedure codes listed above for the following diagnoses, Incomplete spontaneous abortion without complication, Complete or unspecified spontaneous abortion without complication, Failed attempted termination of pregnancy without complication, Supervision of pregnancy with history of infertility, Supervision of pregnancy with history of ectopic pregnancy, Supervision of pregnancy with history of molar pregnancy, Supervision of pregnancy with history of pre-term labor, Supervision of pregnancy with other poor reproductive or obstetric history, Supervision of pregnancy with insufficient antenatal care, Supervision of elderly primigravida and multigravida, Supervision of other or unspecified high risk pregnancy, Pre-existing essential hypertension complicating pregnancy, Pre-existing hypertensive heart disease complicating pregnancy, Pre-existing hypertensive chronic kidney disease complicating pregnancy, Pre-existing hypertensive heart and chronic kidney disease complicating pregnancy, Pre-existing secondary hypertension complicating pregnancy, Unspecified pre-existing hypertension complicating pregnancy, Pre-existing hypertension with pre-eclampsia; first, second or third trimester, Pre-existing hypertension with pre-eclampsia; unspecified trimester, Mild to moderate pre-eclampsia; unspecified, second or third trimester, Severe pre-eclampsia; unspecified, second or third trimester, HELLP syndrome; unspecified, second or third trimester, Unspecified pre-eclampsia; unspecified, second or third trimester, Unspecified maternal hypertension; first, second or third trimester, Unspecified maternal hypertension; unspecified trimester, Pre-existing diabetes mellitus, type 1, in pregnancy, Pre-existing diabetes mellitus, type 2, in pregnancy, Unspecified pre-existing diabetes mellitus in pregnancy, Gestational diabetes mellitus in pregnancy, Other pre-existing diabetes mellitus in pregnancy, Unspecified diabetes mellitus in pregnancy, Pregnancy care for patient with recurrent pregnancy loss, Retained intrauterine contraceptive device in pregnancy, Uterine size-date discrepancy complicating pregnancy, Complications specific to multiple gestation, Maternal care for malpresentation of fetus, Maternal care for abnormality of pelvic organs, Maternal care for known or suspected fetal abnormality and damage, Maternal care for known or suspected poor fetal growth, Maternal care for viable fetus in abdominal pregnancy, Pregnancy with inconclusive fetal viability, Maternal care for abnormalities of the fetal heart rate or rhythm, Maternal care for other specified fetal problems, Maternal care for fetal problem, unspecified, Other disorders of amniotic fluid and membranes, Fetus-to-fetus placental transfusion syndrome, Morbidly adherent placenta, other/unspecified placental disorder, Premature separation of placenta (abruptio placentae), Retained placenta and membranes, without hemorrhage, Abnormality in fetal heart rate and rhythm complicating labor and delivery, Other specified diseases and conditions complicating pregnancy, Contact with and (suspected) exposure to Zika virus. 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